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  1. Contributors/

Prof. Dr. sc. hum. Christian Paret

Principal investigator

Central Institute of Mental Health, Mannheim, and Faculty of Medicine, Ruprecht-Karls University Heidelberg

0000-0002-9225-7182

Christian Paret

Research group leader, research assistant

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Projects


B03: A process-based brain-computer interface to modulate aggressive behavior – a real-time fMRI neurofeedback study

Probe the self-regulation of CS networks in adults and adolescents diagnosed with mental disorders related to frequent stress-associated affective outbursts and aggressive symptoms in posttraumatic stress disorder (PTSD), and BPD. The patients will subsequently be trained to regulate the frontal control network to varying acute threat in a double-blind, randomized, controlled design. An immersive, virtual brain- computer-interface (BCI) will allow for a culture- and age-sensitive, personalized training approach. The aim of the present investigation is to assess feasibility of the approach according to four clinical markers: Reduction of perceived threat and aggressive behavior in daily life, improved control in the face of unfair provocation, and neurofeedback-specific modulation of the neural networks.

Sites


Heidelberg University

Heidelberg University is Germany’s oldest university, founded in 1386. Renowned for its research excellence and strong emphasis on the humanities, natural sciences, and medicine, it consistently ranks among Europe’s top universities. The university fosters a rich academic tradition and an international outlook, attracting students and scholars from around the world.

Central Institute of Mental Health

The Central Institute of Mental Health (Zentralinstitut für Seelische Gesundheit) in Mannheim, Germany, is a leading psychiatric research institution affiliated with Heidelberg University. It specializes in research, treatment, and education related to mental health disorders, neuroscience, and psychosocial factors influencing mental well-being. The institute plays a crucial role in advancing psychiatric knowledge and developing innovative therapies through interdisciplinary collaboration and state-of-the-art facilities.