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  1. Contributors/

Dr. rer. medic. Carmen Weidler

Principal investigator

Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH Aachen University

0000-0002-6547-2776

Carmen Weidler

Carmen Weidler is a neuroscientist whose research primarily focuses on the neural underpinnings of aggressive and impulsive behavior. Her work explores the effects of brain stimulation techniques, such as transcranial direct current stimulation (tDCS), on behavioral and neural correlates of aggression and impulsivity in violent criminal offenders, patients with mental disorders, and healthy individuals. The primary aim of her research is to achieve a better understanding of the individual and methodological factors that enhance the efficacy of tDCS.

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Projects

B01: Neurobehavioral effects of repetitive prefrontal transcranial direct current stimulation (tDCS) on pathological aggression

Carmen Weidler Andreas Reif RWTH Aachen Goethe University Frankfurt Cognitive system Biological Psychiatry Clinical Psychiatry, Psychotherapy, Child and Adolescent Psychiatry
TDCS will be used as an interventional tool to decrease aggression. Using a simultaneous tDCS – fMRI approach, the project aims to enhance cognitive control by repeated prefrontal brain stimulation, investigating its effect on aggression. In addition to gauging tDCS responsivity, identifying the role of individual factors such as genetic profiles in aggression will be a particular focus of this project. By examining brain activity at multiple time points (e.g., before, during multiple stimulation sessions and after tDCS), it will add to the understanding of mechanisms underlying neural tDCS effects and help to identify individual factors that predict responsiveness to the stimulation. To determine the therapeutic potential, we will include psychiatric patients with substance use problems, a group of criminal, violent offenders, and healthy matched controls.

Sites

RWTH Aachen

Natalia Chechko Thomas Frodl Ute Habel Kerstin Konrad Klaus Mathiak Vanessa Reindl Marc Spehr Lisa Wagels Carmen Weidler Jana Zweerings Christiane Licht Christina Neczewicz Nick Worm

RWTH Aachen University is one of Europe’s leading institutions for science and engineering education. Renowned for its strong emphasis on research and innovation, RWTH Aachen collaborates closely with industry and is part of the prestigious IDEA League. The university offers a wide range of programs and is known for its cutting-edge facilities and interdisciplinary approach to solving global challenges.